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Other models in neurons have shown that BHB improves the efficiency of mitochondrial respiration by increasing the ratio of oxidized-to-reduced nicotinamide adenine dinucleotide (NAD + /NADH), thereby leading to a decrease in reactive oxygen species and the blunting of cell death induced by glutamate excitotoxicity (102, 103)
This partial antagonism suggested that the dipeptides action might involve a less specific or weaker interaction with opioid receptors compared to the longer fragments [1]
Patients managing chronic conditions may also consider this therapy as part of a comprehensive functional medicine approach that addresses underlying biochemical imbalances
10.1016/j.sleep.2024.08.012 118 KimS
Per the company's published materials, the logic of the formula runs as follows: butyrate is the preferred fuel source for colonocytes (the cells lining the colon)
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