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It has been reported that treatment with UK-5099, an inhibitor of mitochondrial pyruvate carrier (MPC), reduces the cellular GSH level by diverting glutamine metabolism from GSH synthesis in tumor cells 37

Principal component analysis (PCA), an unsupervised multivariate analysis, was used to discover general trends toward metabolomics data

AlqahtaniTDeoreSLKideAAShendeBASharmaRChakoleRDet alMitochondrial dysfunction and oxidative stress in Alzheimers disease, and Parkinsons disease, huntingtons disease and amyotrophic lateral sclerosis-an updated review

Extended interruptions of multiple days warrant protocol reassessment

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