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NAMPT has been proposed as a potent oncogene capable of promoting cell proliferation by increasing the NAD + pool and, consequently, enhancing SIRT1 and PARP1 activation

doi: 10.1139/y95-146

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Metabolomic profiling was performed at Metabolomics Core, Lurie Cancer Center, Northwestern University, Chicago

Among these, LDL-C is a major contributor to cholesterol deposition within arterial walls and the development of atherosclerosis [40], whereas HDL-C plays a crucial role in reverse cholesterol transport, helping to reduce cardiovascular risk [41]