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6 Conclusions A new form of cell death, termed ferroptosis, was initially characterized in 2012 as distinct from apoptosis and autophagy

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TPO is a key enzyme in the synthesis of thyroid hormone responsible for catalytic oxidation of iodine and iodization of tyrosine, and inhibition of TPO activity can directly lead to reduced thyroid hormone synthesis (Godlewska and Banga, 2019)

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