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Bioavailability is usually determined by calculating the respective plasma drug exposure assessed as the total area under the drug plasma concentration versus time curve (AUC) after oral and intravenous administration as: In general, determinants of oral drug bioavailability include fraction of dose absorbed in the gastrointestinal tract (GIT) and fraction of dose that escapes elimination by the intestinal tract, liver, and lung

Meto provides evidence-based metabolic and hormonal care that addresses those foundations first

[Abstract]2020 Jul;190(1):52-66

10.1172/JCI120849 J

PRP helps interrupt this process by signaling anti-inflammatory repair