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171 GWAS in major populations consistently highlight urate transporter genes as pivotal loci influencing serum uric acid levels, 138,139 notably SLC2A9 (GLUT9) and SLC22A12 (URAT1), involved in urate reabsorption from urinary filtrates

FDA-2013-P-0435)

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Experts think that some people have genes that make them more likely to get Buerger disease