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After the recovery of cellular redox homeostasis, KEAP1 translocates into the nucleus through Karyopherin 6 (importin 7), inducing NRF2 nuclear export to the cytosol, in a CRM1-dependent process through Nuclear Export Signal (NES) sequences present in NRF2

All these evidences suggest that Spirulina may be useful to improve animal and human health changing the gut microbiota composition and promoting beneficial batcterial growth

The significant differences noted in overall metabolism of oral l-carnitineTMA/TMAO in omnivores and, to a lower extent, in vegans/vegetarians are a striking finding

Human data vary by peptide and population

Acetyl L-carnitine (ALC), the acetylated form of the amino acid L-carnitine, is known for its high absorption, stability and bioavailability compared to normal carnitine