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Hypothesis to be tested In Nepalese women, daily supplementation of 50 g vitamin B 12 from early pregnancy, not later than week 15, and until 6 months postpartum, improves linear and ponderal growth as well as cognitive, language and/or motor scores of the Bayley Scales of Infant and Toddler Development, Third Edition (Bayley-III) in their infants

Medications can cause drug-induced autoimmune hepatitis

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The symptoms more likely reflect medication intolerance requiring dose adjustment and supportive care rather than vitamin supplementation

Maintenance therapy typically requires monthly 1000 mcg doses