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On the other hand, in another study of PSD, a high dose of caffeine impairs memory and leads to an anxiogenic and depressive-like behavior in the hole board and elevated plus maze tests, and social interaction and locomotor activity, respectively, also increased pro-inflammatory cytokines such as TNF-alpha and IL-6 [37]

DSIPs role in lowering stress responses and supporting nervous system balance means that in the morning after better sleep, you may feel more centered, emotionally resilient, and mentally sharper

Exclusion criteria were: (a) in-vitro RCTs

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not sure it helps yet, Im also on intermittent fasting and losing about 2 lbs a week Great so far