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Glutathione is a tripeptide naturally synthesised in the liver, where it plays a role in antioxidant defence and cellular detoxification

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These findings, and similar observations of excitotoxic resistance in astrocytes (Rothman, 1984), are supported by RNA-seq data, showing the dominance of GluA2 (inhibits permeability of Ca 2+ ) in both cortical and hippocampal astrocytes in situ (Mlders et al., 2018)

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